BDBM50557604 CHEMBL4745837

SMILES CC1(COC1)N1CCC(CC1)c1cc2n(ncc2cc1C#N)-c1cnn(c1)C1CC1

InChI Key InChIKey=DQPSJOUIIJWLOZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50557604   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50557604(CHEMBL4745837)
Affinity DataIC50: 0.625nMAssay Description:Inhibition of recombinant human GST tagged LRRK2 G2019S mutant catalytic domain (970 to 2527 residues) expressed in baculovirus expression system usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed