BDBM50557845 CHEMBL4756236::WO2021067859, Compound I-9A

SMILES ONC(=O)c1cnc(N[C@H](C2CC2)c2ccccn2)c(F)c1

InChI Key InChIKey=QIGZXLUBHSVIMS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557845   

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM50557845(CHEMBL4756236 | WO2021067859, Compound I-9A)
Affinity DataIC50: 0.351nMAssay Description:Table 14: The compounds disclosed herein, in particular those of Formula (II), were synthesized according to methods disclosed in WO2021067859, which...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/19/2024
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Tenaya Therapeutics

US Patent
LigandPNGBDBM50557845(CHEMBL4756236 | WO2021067859, Compound I-9A)
Affinity DataIC50: 0.351nMAssay Description:Inhibition of recombinant HDAC6 (unknown origin) using luminescent substrate by HDAC-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed