BDBM50557858 CHEMBL4786582

SMILES Clc1cccc(Nc2nn3c(Cn4ccc5ncccc45)nnc3s2)c1

InChI Key InChIKey=YJMJECMHHOSQGD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50557858   

TargetHepatocyte growth factor receptor(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50557858(CHEMBL4786582)
Affinity DataKi:  40nMAssay Description:Inhibition of c-Met (unknown origin) using poly Glu-Tyr as substrate preincubated for 10 mins followed by ATP addition by phosphoenolpyruvate/pyruvat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetHepatocyte growth factor receptor(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50557858(CHEMBL4786582)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of c-MET in human SNU-5 cells measured after 6 hrs by steady-glo luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed