BDBM50558065 CHEMBL4780530

SMILES C[C@@H]1CN(c2ccc(Cl)cc2)c2cc(ccc2-n2c(C)nnc12)-c1ccc(N)nc1

InChI Key InChIKey=SBRJLPKKZHHGCO-CQSZACIVSA-N

Data  16 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 16 hits for monomerid = 50558065   

TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  15nMAssay Description:Inhibition of His/FLAG-tagged BRD4 BD1 (unknown origin) using histone H4-TetraAcetylated-biotin peptide as substrate incubated for 20 mins by AlphaLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 1(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BRD1 (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetPeregrin(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BRPF1 (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 4(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRD4 BD2 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetBromodomain-containing protein 2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRD2 BD1 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRD2 BD2 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 3(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRD3 BD1 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 3(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRD3 BD2 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain testis-specific protein(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRDT BD1 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain testis-specific protein(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  3nMAssay Description:Inhibition of BRDT BD2 (unknown origin) using biotinylated JQ1 analog as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetATPase family AAA domain-containing protein 2(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of His-tagged ATAD2 (unknown origin) using biotinylated acetylated peptide as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain-containing protein 9(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of His-tagged BRD9 (unknown origin) using biotinylated acetylated peptide as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetBromodomain and PHD finger-containing protein 3(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BRPF3 (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetTranscription activator BRG1(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of His-tagged BRG1 (unknown origin) using biotinylated acetylated peptide as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetNucleosome-remodeling factor subunit BPTF(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50: >1.50E+4nMAssay Description:Inhibition of BPTF (unknown origin) measured after 70 mins by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed

TargetCREB-binding protein(Human)
Constellation Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50558065(CHEMBL4780530)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of His-tagged CBP (unknown origin) using biotinylated acetylated peptide as substrate measured after 20 mins by AlphaLISA assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed