BDBM50558122 CHEMBL4764950

SMILES COc1cccc([C@@H]2CC(=NN2c2ccc(cc2)S(N)(=O)=O)c2sc(nc2C)-c2ccccc2)c1OC

InChI Key InChIKey=GGRWEHVYGXFMCS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50558122   

TargetProstaglandin G/H synthase 2(Sheep)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50558122(CHEMBL4764950)
Affinity DataIC50: 3.21E+3nMAssay Description:Inhibition of Ovine COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate pretreated for 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50558122(CHEMBL4764950)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of Ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate pretreated for 15 mins followed by sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed