BDBM50559342 CHEMBL4793731

SMILES CN1CCN(CCCOc2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)CC1

InChI Key InChIKey=IOOAKJXOWGDLDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559342   

TargetReceptor tyrosine-protein kinase erbB-2(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559342BDBM50559342(CHEMBL4793731)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of HER2 (unknown origin) in presence of substrate incubated for 30 mins by ADP-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/27/2022
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Texas A&M University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50559342BDBM50559342(CHEMBL4793731)
Affinity DataIC50: 12nMAssay Description:Inhibition of 1,10-phenanthrolin-induced HIF1 activation in human T47D cells expressing pGL3 construct after 16 hrs by cell-based luciferase reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details PubMed