BDBM50559408 CHEMBL4763773
SMILES COc1cc(OC)c(F)c(CCc2cnc(Nc3ccc(N4CCC(CC4)N4CCN(C)CC4)c(OC)c3)nc2)c1F
InChI Key InChIKey=ZUURNUDMSWVVCL-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50559408
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR3 (436 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...More data for this Ligand-Target Pair
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR1 (398 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG channel expressed in CHO cells at -80 mV holding potential by Qpatch clamp methodMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR4 (460 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astellas Pharma
Curated by ChEMBL
Astellas Pharma
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human N-terminal GST-tagged VEGFR2 (790 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human N-terminal GST-tagged FGFR2 (399 to end residues) expressed in baculovirus expression system using CSKtide as substrate incubated...More data for this Ligand-Target Pair