BDBM50559518 CHEMBL4787524

SMILES CCCn1nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(Cc2ccc(OC(C)C)cc2)c1C

InChI Key InChIKey=IFJMLDQRJZAXGJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50559518   

TargetSodium/glucose cotransporter 2(Human)
Toho University

Curated by ChEMBL
LigandPNGBDBM50559518(CHEMBL4787524)
Affinity DataIC50: 66nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Toho University

Curated by ChEMBL
LigandPNGBDBM50559518(CHEMBL4787524)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction in [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed