BDBM50560227 CHEMBL4747041

SMILES COc1cc2OC(C)(CC(=O)NCCCCCCCNc3c4CCCCc4nc4cc(Cl)ccc34)CCc2cc1OCc1ccccc1

InChI Key InChIKey=JYPJKGLZUCPORL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50560227   

TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50560227(CHEMBL4747041)
Affinity DataIC50:  7nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate preincubated for 15 mins followed by subst...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50560227(CHEMBL4747041)
Affinity DataIC50:  1.25E+4nMAssay Description:Inhibition human BACE1 expressed in baculovirus expression system using Panvera peptide as substrate measured after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
University Of Barcelona (Ub)

Curated by ChEMBL
LigandPNGBDBM50560227(CHEMBL4747041)
Affinity DataIC50:  51nMAssay Description:Inhibition of recombinant human BChE using butyrylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed