BDBM50560485 CHEMBL4779451

SMILES Fc1ccc(cc1)-c1cccc(c1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)NC1(CC1)C#N

InChI Key InChIKey=VQLRPZQZJBYNGY-QHCPKHFHSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50560485   

TargetCathepsin S(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50560485(CHEMBL4779451)
Affinity DataKi:  30nMAssay Description:Inhibition of recombinant human cathepsin S expressed in insect cells using Z-Phe-Arg-AMC as substrate measured after 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50560485(CHEMBL4779451)
Affinity DataKi:  320nMAssay Description:Inhibition of human cathepsin L using Phe-Arg-pNA as substrate measured after 60 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50560485(CHEMBL4779451)
Affinity DataKi:  820nMAssay Description:Inhibition of recombinant human cathepsin K expressed in insect cells using Z-Leu-Arg-AMC as substrate measured after 60 mins by fluorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50560485(CHEMBL4779451)
Affinity DataKi:  3.08E+4nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA as substrate measured after 60 mins by spectrophotometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed