BDBM50561279 CHEMBL4776833

SMILES COc1cccc(Nc2nc3CCSCc3c(Oc3cccc(NC(=O)C=C)c3)n2)c1

InChI Key InChIKey=PGEUNGPQYYKVCP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50561279   

TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50561279(CHEMBL4776833)
Affinity DataIC50: 638nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) using FAM-labelled peptide as substrate incubated for 10 mins in presence of ATP by Kinase Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50561279(CHEMBL4776833)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) using FAM-labelled peptide as substrate incubated for 10 mins in presence of ATP by Kinase Glo luminesc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Jiangxi Science & Technology Normal University

Curated by ChEMBL
LigandPNGBDBM50561279(CHEMBL4776833)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) using FAM-labelled peptide as substrate incubated for 10 mins fin presence of ATP by Kinase Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed