BDBM50561282 CHEMBL4780534

SMILES COc1ccc(Nc2nc3CCSCc3c(Oc3cccc(NC(=O)C=C)c3)n2)cc1

InChI Key InChIKey=MXQIWUCOUMEFAW-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50561282   

TargetEpidermal growth factor receptor(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50561282(CHEMBL4780534)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant EGFR (unknown origin) using TMB as substrate incubated for 3 hrs in presence of ATP by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50561282(CHEMBL4780534)
Affinity DataIC50: 132nMAssay Description:Inhibition of EGFR T790M/L858R mutant (unknown origin) using FAM-labelled peptide as substrate incubated for 10 mins in presence of ATP by Kinase Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50561282(CHEMBL4780534)
Affinity DataIC50: 542nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) using FAM-labelled peptide as substrate incubated for 10 mins fin presence of ATP by Kinase Glo lumi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50561282(CHEMBL4780534)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of wild type EGFR (unknown origin) using FAM-labelled peptide as substrate incubated for 10 mins in presence of ATP by Kinase Glo luminesc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed