BDBM50561513 CHEMBL4759650

SMILES Fc1c(Nc2ncnc3cc4OCCOc4cc23)cccc1C(F)(F)F

InChI Key InChIKey=CZFKRMGQEUSPRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561513   

TargetEpidermal growth factor receptor(Human)
University of California, Los Angeles

Curated by ChEMBL
LigandPNGBDBM50561513(CHEMBL4759650)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant EGFR expressed in baculovirus infected Sf9 insect cells using poly (Glu, Tyr) 4:1 peptide as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of California, Los Angeles

Curated by ChEMBL
LigandPNGBDBM50561513(CHEMBL4759650)
Affinity DataIC50: 55nMAssay Description:Inhibition of wild type EGFR in human U87 cells assessed as heparin/human EGF stimulated phosphorylation after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed