BDBM50561522 CHEMBL4793944

SMILES Fc1c(Br)cc(Cl)cc1Nc1ncnc2cc3OCCOc3cc12

InChI Key InChIKey=MZAWKOMVQFIOTR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561522   

TargetEpidermal growth factor receptor(Human)
University of California, Los Angeles

Curated by ChEMBL
LigandPNGBDBM50561522(CHEMBL4793944)
Affinity DataIC50: 783nMAssay Description:Inhibition of human recombinant EGFR expressed in baculovirus infected Sf9 insect cells using poly (Glu, Tyr) 4:1 peptide as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
University of California, Los Angeles

Curated by ChEMBL
LigandPNGBDBM50561522(CHEMBL4793944)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of wild type EGFR in human U87 cells assessed as heparin/human EGF stimulated phosphorylation after 1 hr by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed