BDBM50561768 CHEMBL4753544

SMILES OCCNC(=O)Nc1nc(N2CCOCC2)c2ccccc2n1

InChI Key InChIKey=JHIFDUYSGVHVCI-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561768   

TargetSerine/threonine-protein kinase mTOR(Human)
Temple University

Curated by ChEMBL

LigandBDBM50561768(CHEMBL4753544)Copy SMILESCopy InChI

Affinity DataIC50: 87nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University

Curated by ChEMBL

LigandBDBM50561768(CHEMBL4753544)Copy SMILESCopy InChI

Affinity DataIC50: 185nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL