BDBM50561770 CHEMBL4751402

SMILES O=C(Nc1cncnc1)Nc1nc(N2CCOCC2)c2ccccc2n1

InChI Key InChIKey=VAYBREBDFXCUMA-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561770   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University

Curated by ChEMBL

LigandBDBM50561770(CHEMBL4751402)Copy SMILESCopy InChI

Affinity DataIC50: 114nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetSerine/threonine-protein kinase mTOR(Human)
Temple University

Curated by ChEMBL

LigandBDBM50561770(CHEMBL4751402)Copy SMILESCopy InChI

Affinity DataIC50: 115nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL