BDBM50561780 CHEMBL4749535

SMILES O=C(Nc1ccc(cc1)S(=O)(=O)Nc1nccs1)Nc1nc(N2CCOCC2)c2ccccc2n1

InChI Key InChIKey=DEWWEOOVJREFIM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50561780   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Temple University

Curated by ChEMBL

LigandBDBM50561780(CHEMBL4749535)Copy SMILESCopy InChI

Affinity DataIC50: 26nMAssay Description:Inhibition of human PI3K p110alpha/p85alpha using PIP2 as substrate incubated for 10 mins followed by ATP addition and measured after 30 mins in pres...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
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TargetSerine/threonine-protein kinase mTOR(Human)
Temple University

Curated by ChEMBL

LigandBDBM50561780(CHEMBL4749535)Copy SMILESCopy InChI

Affinity DataIC50: 83nMAssay Description:Inhibition of human mTOR using 4EBP1 as substrate after 120 mins by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL