BDBM50561788 CHEMBL4793308

SMILES CN1C(=O)N(Cc2cn(CCOCCn3cc(CN4C(c5ccccc5)c5cc(ccc5N(C)C4=O)-c4c(C)noc4C)nn3)nn2)C(c2ccccc2)c2cc(ccc12)-c1c(C)noc1C

InChI Key InChIKey=UXTWDZUHQHUONL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50561788   

TargetBromodomain-containing protein 4(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50561788(CHEMBL4793308)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of BRD4 bromodomain1 (unknown origin) using peptide histone H4 (SGRGACKGGACKGLGAC-KGGAACKRHGSGSK-biotin) as substrate incubated for 15 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed