BDBM50562346 CHEMBL4791280

SMILES C[C@H]1COCCN1c1nc(nn2cc(CN3CCN(CC3)S(C)(=O)=O)cc12)-c1cnc(N)cc1C(F)(F)F

InChI Key InChIKey=AFUFOYSAHFAROX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50562346   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Chinese Academy of Sciences

Curated by ChEMBL

LigandBDBM50562346(CHEMBL4791280)Copy SMILESCopy InChI

Affinity DataIC50: 51nMAssay Description:Inhibition of human PI3Kalpha using PIP2 as substrate in presence of ATP measured after 30 mins by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/28/2022
Entry Details Article
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