BDBM50562358 CHEMBL4787567

SMILES CCCNC(=N)Nc1ccc(Cc2ccc(NC3=NCCN3)nc2)cc1

InChI Key InChIKey=UFVSFWQCSISIPB-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50562358   

TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50562358(CHEMBL4787567)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]-RX821002 from adrenergic alpha 2 receptor in human brain membrane by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed
TargetAlpha-2A/Alpha-2B/Alpha-2C adrenergic receptor(Human)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50562358(CHEMBL4787567)
Affinity DataEC50:  4.14E+3nMAssay Description:Antagonist activity at adrenergic alpha 2 receptor in human brain membrane assessed as inhibition of UK14304-induced stimulation of [35S]GTPgammaS bi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed