BDBM50562641 CHEMBL4754887

SMILES C=CC(=O)N1CCN(c2nc(=O)n(-c3c(C)ccnc3C(C)C)c3c(F)c(-c4c(O)cccc4F)ncc23)[C@@H](C)C1

InChI Key InChIKey=BMYLNWKIHCJFRN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50562641   

TargetGTPase KRas(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562641BDBM50562641(CHEMBL4754887)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KRAS (2 to 185 residues) expressed in baculovirus infected Sf9 insect cells using GTP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562641BDBM50562641(CHEMBL4754887)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KRAS (2 to 185 residues) expressed in baculovirus infected Sf9 insect cells using GTP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGTPase KRas(Human)
Shanghai Institute of Materia Medica (Simm)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50562641BDBM50562641(CHEMBL4754887)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human N-terminal His-tagged KRAS (2 to 185 residues) expressed in baculovirus infected Sf9 insect cells using GTP as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed