BDBM50562662 CHEMBL4741456

SMILES COc1ccc(Nc2cc(cc3c4ccccc4[nH]c(=O)c23)-c2cccs2)cc1

InChI Key InChIKey=JCAULMHEVXFBGL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50562662   

Target72 kDa type IV collagenase(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562662(CHEMBL4741456)
Affinity DataIC50:  6.05E+3nMAssay Description:Inhibition of recombinant human MMP2 (110 to 452 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in yeast expression system as substrat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCollagenase 3(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562662(CHEMBL4741456)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of recombinant human MMP13 (104 to 274 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562662(CHEMBL4741456)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of recombinant human MMP9 (107 to 449 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Human)
Universidad Complutense

Curated by ChEMBL
LigandPNGBDBM50562662(CHEMBL4741456)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant human MMP8 (99 to 269 residues) using Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 expressed in Escherichia coli expression system a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed