BDBM50563091 CHEMBL4780210

SMILES Cc1nn(-c2ccccc2)c2nc([nH]c(=O)c12)C(=O)N1NC(=O)\C(=C\c2ccc(Cl)cc2)N=C1c1ccc(C)cc1

InChI Key InChIKey=KJUSPADQYSCMML-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563091   

TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50563091(CHEMBL4780210)
Affinity DataIC50: 1.89E+3nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50563091(CHEMBL4780210)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed