BDBM50563092 CHEMBL4790553

SMILES Cc1nn(-c2ccccc2)c2nc(CC(=O)N3NC(=O)\C(=C/c4ccccc4)N=C3c3ccccc3)[nH]c(=O)c12

InChI Key InChIKey=WQBUHXFDAFUDSU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563092   

TargetEpidermal growth factor receptor(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50563092(CHEMBL4790553)
Affinity DataIC50: 656nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50563092(CHEMBL4790553)
Affinity DataIC50: 872nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed