BDBM50563239 CHEMBL4758183

SMILES Clc1cc(Br)cc(NC(=O)[C@@H]2CSCCC(=O)N2)c1

InChI Key InChIKey=BYVAPGOEUAONCD-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50563239   

TargetMetabotropic glutamate receptor 4(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50563239(CHEMBL4758183)
Affinity DataEC50:  33nMAssay Description:Positive allosteric modulation of rat mGlu4 receptor expressed in HEK293 cells co- expressing GIRK channel by thallium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 7(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50563239(CHEMBL4758183)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to mGlu7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50563239(CHEMBL4758183)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]quisqualate from mGluR1 from rat brain incubated for 60 mins by radiometric scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50563239(CHEMBL4758183)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]LY341495 from full length human recombinant mGluR2 expressed in Chem-1 cells incubated for 60 mins by radiometric scintillation c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50563239(CHEMBL4758183)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to mGlu3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University

Curated by ChEMBL
LigandPNGBDBM50563239(CHEMBL4758183)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to mGlu5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed