BDBM50563419 CHEMBL4764787

SMILES COc1cc(CNc2nc(NCc3ccc(cc3)C(=O)Nc3ccccc3N)nc3[nH]ccc23)cc(OC)c1

InChI Key InChIKey=ZLMHPLCYVOENBV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50563419   

TargetHistone deacetylase 1(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563419(CHEMBL4764787)
Affinity DataIC50: 160nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563419(CHEMBL4764787)
Affinity DataIC50: 481nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563419(CHEMBL4764787)
Affinity DataIC50: 910nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563419(CHEMBL4764787)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50563419(CHEMBL4764787)
Affinity DataIC50: 5.78E+3nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic-(RHKKAc) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed