BDBM50563569 CHEMBL4793363

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)C(=O)Nc1ccccc1

InChI Key InChIKey=RMPAEYMSFVUOJE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563569   

TargetProteasome subunit beta type-8(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563569(CHEMBL4793363)
Affinity DataIC50: 35nMAssay Description:Inhibition of 20S immunoproteasome beta 5 chymotrypsin-like activity in human H226 cell using Suc-LLVY-AMC as substrate for 10 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563569(CHEMBL4793363)
Affinity DataIC50: 381nMAssay Description:Inhibition of 20S immunoproteasome beta 2 trypsin-like activity in human H226 cell using Z-LRR-aminoluciferin as substrate for 10 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563569(CHEMBL4793363)
Affinity DataIC50: 611nMAssay Description:Inhibition of 20S immunoproteasome beta 1 caspase-like activity in human H226 cell using Z-nLPnLD-aminoluciferin as substrate for 10 mins by fluoresc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed