BDBM50563578 CHEMBL4743601

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)C(=O)Nc1cccc(c1)C(C)=O

InChI Key InChIKey=NZVFNFWVRSOYCM-IMKBVMFZSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563578   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563578(CHEMBL4743601)
Affinity DataIC50:  30nMAssay Description:Inhibition of 20S immunoproteasome beta 5 chymotrypsin-like activity in human H226 cell using Suc-LLVY-AMC as substrate for 10 mins by fluorescence b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563578(CHEMBL4743601)
Affinity DataIC50:  1.21E+3nMAssay Description:Inhibition of 20S immunoproteasome beta 1 caspase-like activity in human H226 cell using Z-nLPnLD-aminoluciferin as substrate for 10 mins by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563578(CHEMBL4743601)
Affinity DataIC50:  469nMAssay Description:Inhibition of 20S immunoproteasome beta 2 trypsin-like activity in human H226 cell using Z-LRR-aminoluciferin as substrate for 10 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed