BDBM50563587 CHEMBL4765143

SMILES COc1cc(NC(=O)C(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc2ccccc2)cc(OC)c1

InChI Key InChIKey=FGRSAQAHQRODRU-DTXPUJKBSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50563587   

TargetProteasome subunit beta type-8(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563587(CHEMBL4765143)
Affinity DataIC50:  26nMAssay Description:Inhibition of 20S immunoproteasome beta 5 chymotrypsin-like activity in human H226 cell using Suc-LLVY-AMC as substrate for 10 mins by fluorescence b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563587(CHEMBL4765143)
Affinity DataIC50:  361nMAssay Description:Inhibition of 20S immunoproteasome beta 1 caspase-like activity in human H226 cell using Z-nLPnLD-aminoluciferin as substrate for 10 mins by fluoresc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563587(CHEMBL4765143)
Affinity DataIC50:  168nMAssay Description:Inhibition of 20S immunoproteasome beta 2 trypsin-like activity in human H226 cell using Z-LRR-aminoluciferin as substrate for 10 mins by fluorescenc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed