BDBM50563590 CHEMBL4753369

SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)c2ccc(o2)-c2ccc(cc2)C(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)C(=O)Nc2cccc(OC)c2)cc1

InChI Key InChIKey=PKWKINMZSJOFKI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50563590   

TargetProteasome subunit beta type-8(Human)
Tsinghua University

Curated by ChEMBL
LigandPNGBDBM50563590(CHEMBL4753369)
Affinity DataIC50: 29nMAssay Description:Inhibition of 20S immunoproteasome beta 5 chymotrypsin-like activity in human H226 cell using Suc-LLVY-AMC as substrate for 10 mins by fluorescence b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed