BDBM50563630 CHEMBL4784124

SMILES Cc1cccc(n1)-c1[nH]c(CNc2ccc(F)cc2)nc1-c1ccc2n(C)ncc2c1

InChI Key InChIKey=XYCSMDDTSMSRGN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563630   

TargetTGF-beta receptor type-1(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50563630(CHEMBL4784124)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GST-fused ALK5 expressed in baculovirus infected Sf9 cells assessed as incoporation of [33]Pi after 60 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Yanbian University

Curated by ChEMBL
LigandPNGBDBM50563630(CHEMBL4784124)
Affinity DataIC50: 112nMAssay Description:Inhibition of recombinant human p38alpha expressed in Escherichia coli assessed as incoporation of [33]Pi after 60 mins in presence of [gamma-33P]-AT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed