BDBM50563775 CHEMBL4789165

SMILES CCCCCn1cc(nc1N)-c1ccc(F)cc1

InChI Key InChIKey=QZJQAKIEBJSRFN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50563775   

TargetToll-like receptor 8(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50563775(CHEMBL4789165)
Affinity DataEC50:  1.96E+3nMAssay Description:Agonist activity at human TLR8 (27 to 827 residues) stably expressed in human HEK-Blue hTLR8 cells assessed as activation of NFkappaB by SAP reporter...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetToll-like receptor 8(Human)
Csir-Indian Institute of Chemical Biology

Curated by ChEMBL
LigandPNGBDBM50563775(CHEMBL4789165)
Affinity DataEC50:  1.96E+3nMAssay Description:Agonist activity at human TLR8 stably expressed in HEK293 cells cotransfected with secreted alkaline phosphatase assessed as induction of NFkappaB ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed