BDBM50564012 CHEBI:18383::CHEMBL596011::DL-2,3-diaminopropionic acid

SMILES NCC(N)C(O)=O

InChI Key InChIKey=PECYZEOJVXMISF-UHFFFAOYSA-N

Data  4 IC50

PDB links: 10 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50564012   

TargetSodium- and chloride-dependent GABA transporter 1(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50564012(CHEBI:18383 | CHEMBL596011 | DL-2,3-diaminopropion...)
Affinity DataIC50: <1.00E+6nMAssay Description:Inhibition of human GTA1 receptor expressed in tsA201 cells assessed as inhibition of [3H]GABA uptake by liquid scintillation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 3(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50564012(CHEBI:18383 | CHEMBL596011 | DL-2,3-diaminopropion...)
Affinity DataIC50:  3.16E+4nMAssay Description:Inhibition of human GTA3 receptor expressed in tsA201 cells assessed as inhibition of [3H]GABA uptake by liquid scintillation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent GABA transporter 2(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50564012(CHEBI:18383 | CHEMBL596011 | DL-2,3-diaminopropion...)
Affinity DataIC50:  3.98E+4nMAssay Description:Inhibition of human GTA2 receptor expressed in tsA201 cells assessed as inhibition of [3H]GABA uptake by liquid scintillation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium- and chloride-dependent betaine transporter(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50564012(CHEBI:18383 | CHEMBL596011 | DL-2,3-diaminopropion...)
Affinity DataIC50:  6.31E+5nMAssay Description:Inhibition of human BGT1 expressed in tsA201 cells assessed as inhibition of [3H]GABA uptake by liquid scintillation methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed