BDBM50564477 CHEMBL4779958

SMILES Cc1c(NC(=S)Nc2ccc3OCOc3c2)c(=O)n(-c2ccccc2)n1C

InChI Key InChIKey=ZNMSKFVKBVCPAJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50564477   

TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564477(CHEMBL4779958)
Affinity DataIC50: 358nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564477(CHEMBL4779958)
Affinity DataIC50: 8.60E+4nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564477(CHEMBL4779958)
Affinity DataIC50: 4.33E+5nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed