BDBM50564478 CHEMBL4782320

SMILES S=C(Nc1ccc2OCOc2c1)Nc1c2ccccc2nc2ccccc12

InChI Key InChIKey=UXZDJRJJDCBSLW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50564478   

TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564478(CHEMBL4782320)
Affinity DataIC50: 493nMAssay Description:Inhibition of EGFR (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564478(CHEMBL4782320)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
National Research Centre

Curated by ChEMBL
LigandPNGBDBM50564478(CHEMBL4782320)
Affinity DataIC50: 4.62E+5nMAssay Description:Inhibition of EGFR T790M mutant (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed