BDBM50564724 CHEMBL4794102

SMILES CCN1CCN(CC1)c1nc(Oc2ccc3ccc(=O)[nH]c3c2)c2sccc2n1

InChI Key InChIKey=JURSEJSFFCDYSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50564724   

TargetEpidermal growth factor receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50564724(CHEMBL4794102)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of N-terminal GST-fused human EGFR L858R/T790M double mutant cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zhengzhou University

Curated by ChEMBL
LigandPNGBDBM50564724(CHEMBL4794102)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of N-terminal GST-fused human wild type EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using 5-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed