BDBM50564911 CHEMBL4786755

SMILES CC(=O)c1nnn(c1C)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=QJBPFELDRXSCTJ-UHFFFAOYSA-N

Data  4 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50564911   

TargetCarbonic anhydrase 2(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564911(CHEMBL4786755)
Affinity DataKi:  7.90nMAssay Description:Inhibition of human CA2 by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564911(CHEMBL4786755)
Affinity DataKi:  73nMAssay Description:Inhibition of human CA1 by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564911(CHEMBL4786755)
Affinity DataKi:  83nMAssay Description:Inhibition of human CA12 by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564911(CHEMBL4786755)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant COX2 by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564911(CHEMBL4786755)
Affinity DataIC50: 2.61E+3nMAssay Description:Inhibition of COX-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564911(CHEMBL4786755)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of ovine COX1 by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564911(CHEMBL4786755)
Affinity DataKi:  9.12E+3nMAssay Description:Inhibition of human CA9 by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed