BDBM50564912 CHEMBL4786875

SMILES CC(=O)c1nnn(c1C)-c1ccc(cc1)S(=O)(=O)Nc1nccs1

InChI Key InChIKey=YCWRMFSXKNKRJK-UHFFFAOYSA-N

Data  4 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50564912   

TargetProstaglandin G/H synthase 2(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564912(CHEMBL4786875)
Affinity DataIC50: 290nMAssay Description:Inhibition of human recombinant COX2 by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564912(CHEMBL4786875)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of ovine COX1 by colorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564912(CHEMBL4786875)
Affinity DataKi:  6.28E+3nMAssay Description:Inhibition of human CA2 by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564912(CHEMBL4786875)
Affinity DataKi:  5.10E+4nMAssay Description:Inhibition of human CA1 by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564912(CHEMBL4786875)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA9 by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50564912(CHEMBL4786875)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human CA12 by stopped-flow carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed