BDBM50565709 CHEMBL4786463

SMILES COc1cc2c(Oc3ccc(Nc4nccc5[nH]cc(-c6ccc(F)cc6)c(=O)c45)cc3F)ncnc2cc1OCC1CCN(C)CC1

InChI Key InChIKey=LNAOKRMVGJXRHU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565709   

TargetHepatocyte growth factor receptor(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50565709(CHEMBL4786463)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant MET kinase domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Central China Normal University

Curated by ChEMBL
LigandPNGBDBM50565709(CHEMBL4786463)
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant VEGFR2 kinase domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed