BDBM50565758 CHEMBL4782751

SMILES CC(C)[C@@H]1N(CC[C@@]11C(=O)N(c2ccccc12)c1cccc(c1)-c1ccc(C(=O)N(C)C)c(Cl)c1)C(=S)NC(C)(C)C

InChI Key InChIKey=HQPVSZHQXIYMRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50565758   

TargetOxysterols receptor LXR-beta(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50565758(CHEMBL4782751)
Affinity DataIC50: 1.43E+3nMAssay Description:Inverse agonist activity at human LXRbeta transfected in human HEK293T cells co-transfected with pSG5 and pGL3/(DR-4)-c-fos-FF-luc/pCMV/Renilla-luc a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50565758(CHEMBL4782751)
Affinity DataIC50: 2.59E+3nMAssay Description:Inverse agonist activity at human LXRalpha transfected in human HEK293T cells co-transfected with pSG5 and pGL3/(DR-4)-c-fos-FF-luc/pCMV/Renilla-luc ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2022
Entry Details Article
PubMed