BDBM50566146 CHEMBL4786158

SMILES CC1CCN(CC1)c1nc(ccc1CNC(=O)Nc1cccc2n(C)c(=O)ccc12)C(F)(F)F

InChI Key InChIKey=WRMTZTQHCDVWNR-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50566146   

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50566146(CHEMBL4786158)
Affinity DataKi:  0.570nMAssay Description:Displacement of [3H]RTX from human TRPV1 expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetTransient receptor potential cation channel subfamily V member 1(Human)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50566146(CHEMBL4786158)
Affinity DataKi:  2.60nMAssay Description:Antagonist activity at human TRPV1 expressed in CHO cells assessed as inhibition of 30 nM capsaicin-induced calcium uptakeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed