BDBM50566970 CHEMBL4862549

SMILES Nc1nc2cc(ccc2o1)-c1nn(CC2CCN(CC2)c2ncc(cn2)C(=O)NO)c2ncnc(N)c12

InChI Key InChIKey=VPTVCYOEECUFBP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50566970   

TargetSerine/threonine-protein kinase mTOR(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566970(CHEMBL4862549)
Affinity DataIC50: 0.490nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566970(CHEMBL4862549)
Affinity DataIC50: 0.910nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566970(CHEMBL4862549)
Affinity DataIC50: 27nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566970(CHEMBL4862549)
Affinity DataIC50: 86nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Anhui University of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50566970(CHEMBL4862549)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of HDAC11 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed