BDBM50567035 CHEMBL4852682

SMILES C(C1CCNCC1)n1nnc2ccc(cc12)-c1c[nH]c2ccccc12

InChI Key InChIKey=PNWXIFPGKLWYOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50567035   

TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567035(CHEMBL4852682)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human TDO2 expressed in mouse P815B cells assessed as kynurenine concentration formation using L-tryptophan as substrate incubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567035(CHEMBL4852682)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of full length N-terminal/C-terminal his-tagged human TDO expressed in Escherichia coli BL21 (DE3) assessed as N-formylkynurenine formatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Louvain

Curated by ChEMBL
LigandPNGBDBM50567035(CHEMBL4852682)
Affinity DataIC50: 2.55E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed