BDBM50568075 CHEMBL4845877

SMILES CC(C)=CCC1=C(O)c2ccccc2/C(=N/NC(=O)c2ccncc2)C1=O

InChI Key InChIKey=NWXSOEXSTKFJFP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50568075   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568075BDBM50568075(CHEMBL4845877)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCysteine protease(Trypanosoma brucei rhodesiense)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568075BDBM50568075(CHEMBL4845877)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of recombinant Trypanosoma brucei rhodesain using Z-FR-AMC as substrate by fluorimetric analysis relative to controlMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
Federal University of Alagoas

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568075BDBM50568075(CHEMBL4845877)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant Trypanosoma cruzi cruzain using Z-FR-AMC as substrate preincubated for 10 mins followed by substrate addition measured for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed