BDBM50568079 CHEMBL4870635

SMILES CC(C)(F)c1noc(n1)N1CCC(CC1)N(c1cc(OC2CCN(CC2)S(C)(=O)=O)ncn1)C(F)(F)F

InChI Key InChIKey=NTGWXGVFVHJWLL-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50568079   

TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at rat GPR119 in GLUTag cells assessed as induction of GLP-1 secretion after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by ste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at rat GPR119 in golden hamster HIT-T15 cells assessed as induction of glucose-induced insulin secretion after 2 hrs by A1phaLISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50568079(CHEMBL4870635)
Affinity DataEC50:  24nMAssay Description:Agonist activity at rat GPR119 expressed in CHO cells co-expressing cyclic AMP response element-luciferase reporter gene incubated for 2 hrs by stead...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed