BDBM50568105 CHEMBL4858455::US11851436, Compound A1-3

SMILES Oc1c(F)cc(Nc2ncc3ncn(-c4ccc(cc4)N4CCOCC4)c3n2)cc1F

InChI Key InChIKey=AZIATJQXGGRMIL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50568105   

TargetRibosomal protein S6 kinase alpha-3(Human)
The Regents of The University of Colorado, A Body Corporate

US Patent
LigandPNGBDBM50568105(CHEMBL4858455 | US11851436, Compound A1-3)
Affinity DataIC50:  18.4nMAssay Description:LANCE (Lanthanide Chelate Excite) Eu time-resolved fluorescence resonance energy transfer (TR-FRET) kinase assay (PerkinElmer) was performed in 384-w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent


TargetRibosomal protein S6 kinase alpha-3(Human)
The Regents of The University of Colorado, A Body Corporate

US Patent
LigandPNGBDBM50568105(CHEMBL4858455 | US11851436, Compound A1-3)
Affinity DataIC50:  25nMAssay Description:Inhibition of RSK2 (unknown origin) using Ulight-rpS6 as substrate incubated for 1 hr in presence of ATP by TR FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed