BDBM50568215 CHEMBL4878197

SMILES CCC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CC23CCN(CCCCCCCCn2ccc4cc(c(OC)cc4c2=O)-c2cnc1[nH]2)CC3

InChI Key InChIKey=ZUOQPJWZUKPUSH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50568215   

TargetHistone deacetylase 1(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568215BDBM50568215(CHEMBL4878197)
Affinity DataIC50: 0.110nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568215BDBM50568215(CHEMBL4878197)
Affinity DataIC50: 0.130nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568215BDBM50568215(CHEMBL4878197)
Affinity DataIC50: 0.310nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568215BDBM50568215(CHEMBL4878197)
Affinity DataIC50: 218nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Merck

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568215BDBM50568215(CHEMBL4878197)
Affinity DataIC50: 900nMAssay Description:Inhibition of HDAC8 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed