BDBM50568305 CHEMBL4873811

SMILES CN1CCN(CC1)c1nc(nc2cc(Cl)ccc12)-c1ccc(cc1)C(=O)NO

InChI Key InChIKey=DYZSQWJEPPEPAQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50568305   

TargetHistone deacetylase 6(Human)
Harbin Medical University

Curated by ChEMBL
LigandPNGBDBM50568305(CHEMBL4873811)
Affinity DataIC50: 56nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Harbin Medical University

Curated by ChEMBL
LigandPNGBDBM50568305(CHEMBL4873811)
Affinity DataIC50: 134nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Harbin Medical University

Curated by ChEMBL
LigandPNGBDBM50568305(CHEMBL4873811)
Affinity DataIC50: 359nMAssay Description:Inhibition of HDAC1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Harbin Medical University

Curated by ChEMBL
LigandPNGBDBM50568305(CHEMBL4873811)
Affinity DataIC50: 374nMAssay Description:Inhibition of HDAC2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Harbin Medical University

Curated by ChEMBL
LigandPNGBDBM50568305(CHEMBL4873811)
Affinity DataIC50: 414nMAssay Description:Inhibition of HDAC3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed