BDBM50568339 CHEMBL4876147

SMILES OC(=O)c1ccccc1-c1cccc2n(Cc3cccc4ccccc34)cc(-c3cccc(c3)C(F)(F)F)c12

InChI Key InChIKey=YGCPADWESJRXBM-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50568339   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50568339(CHEMBL4876147)
Affinity DataKi:  190nMAssay Description:Binding affinity to Mc1-1 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBcl2-associated agonist of cell death(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50568339(CHEMBL4876147)
Affinity DataKi:  1.08E+3nMAssay Description:Binding affinity to Bcl-2 (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50568339(CHEMBL4876147)
Affinity DataKi: >2.00E+5nMAssay Description:Binding affinity to Bc1-xL (unknown origin) by fluorescence polarization competition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed