BDBM50568641 CHEMBL4852987

SMILES C/C=C1/CN2[C@@H]3C[C@@]45c6ccccc6N[C@]4(O3)[C@@H]2C[C@@H]1[C@@]5(COC(C)=O)C(=O)OC

InChI Key InChIKey=DXTJMQCRVFWNBD-UHFFFAOYSA-N

Data  6 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50568641   

TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataIC50: 1.97E+3nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataIC50: 2.00E+3nMAssay Description:Agonist activity at mouse FLAG-tagged kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataKi:  2.38E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H]-U69593 from human kappa opioid receptor expressed in U2OS cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetD(1B) dopamine receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-SCH23390 from dopamine D5 receptor (unknown origin) expressed in HEK-293T cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Mouse)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataIC50: 4.50E+4nMAssay Description:Agonist activity at mouse HA-tagged mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataKi:  9.88E+4nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataKi:  1.00E+5nMAssay Description:Displacement of [3H]-DPDPE from human delta opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50568641BDBM50568641(CHEMBL4852987)
Affinity DataKi:  1.32E+5nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed